Recombinant Human ALOX12 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ALOX12 Protein, Myc/DDK-tagged, C13 and N15-labeled

ALOX12 Related Products

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Cat.No. : ALOX12-2197H
Product Overview : ALOX12 MS Standard C13 and N15-labeled recombinant protein (NP_000688) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 75.5 kDa
AA Sequence : MGRYRIRVAT GAWLFSGSYN RVQLWLVGTR GEAELELQLR PARGEEEEFD HDVAEDLGLL QFVRLRKHHW LVDDAWFCDR ITVQGPGACA EVAFPCYRWV QGEDILSLPE GTARLPGDNA LDMFQKHREK ELKDRQQIYC WATWKEGLPL TIAADRKDDL PPNMRFHEEK RLDFEWTLKA GALEMALKRV YTLLSSWNCL EDFDQIFWGQ KSALAEKVRQ CWQDDELFSY QFLNGANPML LRRSTSLPSR LVLPSGMEEL RAQLEKELQN GSLFEADFIL LDGIPANVIR GEKQYLAAPL VMLKMEPNGK LQPMVIQIQP PNPSSPTPTL FLPSDPPLAW LLAKSWVRNS DFQLHEIQYH LLNTHLVAEV IAVATMRCLP GLHPIFKFLI PHIRYTMEIN TRARTQLISD GGIFDKAVST GGGGHVQLLR RAAAQLTYCS LCPPDDLADR GLLGLPGALY AHDALRLWEI IARYVEGIVH LFYQRDDIVK GDPELQAWCR EITEVGLCQA QDRGFPVSFQ SQSQLCHFLT MCVFTCTAQH AAINQGQLDW YAWVPNAPCT MRMPPPTTKE DVTMATVMGS LPDVRQACLQ MAISWHLSRR QPDMVPLGHH KEKYFSGPKP KAVLNQFRTD LEKLEKEITA RNEQLDWPYE YLKPSCIENS VTISGPTRTR RLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ALOX12 arachidonate 12-lipoxygenase [ Homo sapiens (human) ]
Official Symbol : ALOX12
Synonyms : ALOX12; arachidonate 12-lipoxygenase; arachidonate 12-lipoxygenase, 12S-type; 12S LOX; platelet 12 LOX; platelet 12-LOX; 12S-lipoxygenase; 12(S)-lipoxygenase; platelet-type 12-lipoxygenase; platelet-type lipoxygenase 12; LOG12; 12-LOX; 12S-LOX;
Gene ID : 239
mRNA Refseq : NM_000697
Protein Refseq : NP_000688
MIM : 152391
UniProt ID : P18054

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