Recombinant Human ALPL Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | ALPL-028H |
Product Overview : | ALPL MS Standard C13 and N15-labeled recombinant protein (NP_000469) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 57.3 kDa |
AA Sequence : | MISPFLVLAIGTCLTNSLVPEKEKD PKYWRDQAQETLKYALELQKLNTNV AKNVIMFLGDGMGVSTVTAARILKG QLHHNPGEETRLEMDKFPFVALSKT YNTNAQVPDSAGTATAYLCGVKANE GTVGVSAATERSRCNTTQGNEVTSI LRWAKDAGKSVGIVTTTRVNHATPS AAYAHSADRDWYSDNEMPPEALSQG CKDIAYQLMHNIRDIDVIMGGGRKY MYPKNKTDVEYESDEKARGTRLDGL DLVDTWKSFKPRYKHSHFIWNRTEL LTLDPHNVDYLLGLFEPGDMQYELN RNNVTDPSLSEMVVVAIQILRKNPK GFFLLVEGGRIDHGHHEGKAKQALH EAVEMDRAIGQAGSLTSSEDTLTVV TADHSHVFTFGGYTPRGNSIFGLAP MLSDTDKKPFTAILYGNGPGYKVVG GERENVSMVDYAHNNYQAQSAVPLR HETHGGEDVAVFSKGPMAHLLHGVH EQNYVPHVMAYAACIGANLGHCAPA SSAGSLAAGPLLLALALYPLSVLFT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ALPL alkaline phosphatase, biomineralization associated [ Homo sapiens (human) ] |
Official Symbol : | ALPL |
Synonyms : | ALPL; alkaline phosphatase, biomineralization associated; AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP; alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, liver/bone/kidney; liver/bone/kidney-type alkaline phosphatase; tissue non-specific alkaline phosphatase; tissue-nonspecific ALP; EC 3.1.3.1 |
Gene ID : | 249 |
mRNA Refseq : | NM_000478 |
Protein Refseq : | NP_000469 |
MIM : | 171760 |
UniProt ID : | P05186 |
Products Types
◆ Recombinant Protein | ||
ALPL-327H | Active Recombinant Human ALPL Protein, His-tagged | +Inquiry |
ALPL-123C | Recombinant Cattle ALPL Protein, His-tagged | +Inquiry |
ALPL-01H | Active Recombinant Human ALPL Protein (18-501aa), C-His-tagged | +Inquiry |
Alpl-5784M | Recombinant Mouse Alpl Protein, His-tagged | +Inquiry |
ALPL-138R | Recombinant Rhesus Macaque ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
ALPL-66C | Active Native Calf Alkaline Phosphatase | +Inquiry |
ALPL-5324H | Active Native Human Alkaline Phosphatase | +Inquiry |
ALPL-8004H | Native Human Liver Alkaline Phosphatase | +Inquiry |
◆ Lysates | ||
ALPL-3092HCL | Recombinant Human ALPL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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