| Description : |
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
42.2 kDa |
| AA Sequence : |
MALQGISVMELSGLAPGPFCAMVLA DFGARVVRVDRPGSRYDVSRLGRGK RSLVLDLKQPRGAAVLRRLCKRSDV LLEPFRRGVMEKLQLGPEILQRENP RLIYARLSGFGQSGSFCRLAGHDIN YLALSGVLSKIGRSGENPYAPLNLL ADFAGGGLMCALGIIMALFDRTRTD KGQVIDANMVEGTAYLSSFLWKTQK SSLWEAPRGQNMLDGGAPFYTTYRT ADGEFMAVGAIEPQFYELLIKGLGL KSDELPNQMSMDDWPEMKKKFADVF AKKTKAEWCQIFDGTDACVTPVLTF EEVVHHDHNKERGSFITSEEQDVSP RPAPLLLNTPAIPSFKRDPFIGEHT EEILEEFGFSREEIYQLNSDKIIES NKVKASLSGPSGPTRTRRLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
