Recombinant Human AMER2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | AMER2-4565H |
Product Overview : | FAM123A MS Standard C13 and N15-labeled recombinant protein (NP_954589) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | AMER2 (APC Membrane Recruitment Protein 2) is a Protein Coding gene. Diseases associated with AMER2 include Osteopathia Striata With Cranial Sclerosis. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol-4,5-bisphosphate binding. An important paralog of this gene is AMER1. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 57.4 kDa |
AA Sequence : | METSRSRGGGGAVSERGGAGASVGV CRRKAEAGAGTGTLAADMDLHCDCA AETPAAEPPSGKINKAAFKLFKKRK SGGTMPSIFGVKNKGDGKSSGPTGL VRSRTHDGLAEVLVLESGRKEEPRG GGDSGGGGGGRPNPGPPRAAGPGGG SLASSSVAKSHSFFSLLKKNGRSEN GKGEPVDASKAGGKQKRGLRGLFSG MRWHRKDKRAKAEAAEGRAPGGGLI LPGSLTASLECVKEETPRAAREPEE PSQDAPRDPAGCGDIIADQEEEAGP SCDKHVPGPGKPALSKKNPGVVAYQ GGGEEMASPDEVDDTYLQEFWDMLS QTEEQGPEPQEGAAKVAAALETKVV PETPKDTRCVEAAKDASSVKRRRLN RIPIEPHPKEEPKHPEKEQQEGVPN SDEGYWDSTTPGPEEDSSSSGKKAG IPRDSYSGDALYDLYADPDGSPATL PGGKDNEETSSLSRLKPVSPGTITC PLRTPGSLLKDSKIPISIKHLTNLP SSHPVVHQQPSRSEMPRTKIPVSKV LVRRVSNRGLAGTTIRATACHDSAK KLSGPTRTRRLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | AMER2 APC membrane recruitment protein 2 [ Homo sapiens (human) ] |
Official Symbol : | AMER2 |
Synonyms : | AMER2; APC membrane recruitment protein 2; FAM123A; APC membrane recruitment protein 2; family with sequence similarity 123A; protein FAM123A |
Gene ID : | 219287 |
mRNA Refseq : | NM_199138 |
Protein Refseq : | NP_954589 |
MIM : | 614659 |
UniProt ID : | Q8N7J2 |
Products Types
◆ Recombinant Protein | ||
Amer2-1610M | Recombinant Mouse Amer2 Protein, Myc/DDK-tagged | +Inquiry |
AMER2-1989H | Recombinant Human AMER2 Protein, MYC/DDK-tagged | +Inquiry |
AMER2-5887Z | Recombinant Zebrafish AMER2 | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAMER2 contributes to specific cellular pathways, such as Wnt signaling, by modulating the activity or localization of key pathway components.
Mutations in AMER2 can impact protein structure and function, potentially affecting its interaction with binding partners or disrupting cellular processes.
AMER2 expression levels vary during different stages of development, with higher expression in certain tissues or cell types.
The expression of AMER2 is regulated by transcription factors, epigenetic modifications, or signaling cascades involved in cell fate determination.
AMER2 knockout or overexpression leads to alterations in cellular processes, such as proliferation, differentiation, or cell migration.
Manipulating AMER2 expression or activity may hold therapeutic potential for certain diseases where dysregulation of cellular processes or signaling pathways is involved.
AMER2 interacts with various cellular proteins or signaling pathways, modulating their activity or participating in protein complexes.
AMER2 influences cellular proliferation and differentiation through its regulatory effects on specific signaling pathways or gene expression programs.
AMER2 protein localizes primarily to the cytoplasm or specific subcellular compartments.
AMER2 protein contains functional domains involved in protein-protein interactions and potential enzymatic activities.
Customer Reviews (3)
Write a reviewReduced assay variability for reliable data interpretation.
High specificity in target protein localization studies.
Minimal assay interference from endogenous inhibitors.
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