Recombinant Human ANG Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ANG-1424H
• Product Overview: ANG MS Standard C13 and N15-labeled recombinant protein (NP_001136) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 16.6 kDa
• AA Sequence: MVMGLGVLLLVFVLGLGLTPPTLAQ DNSRYTHFLTQHYDAKPQGRDDRYC ESIMRRRGLTSPCKDINTFIHGNKR SIKAICENKNGNPHRENLRISKSSF QVTTCKLHGGSPWPPCQYRATAGFR NVVVACENGLPVHLDQSIFRRPTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ANG angiogenin [ Homo sapiens (human) ]
• Official Symbol: ANG
• Synonyms: ANG; angiogenin, ribonuclease, RNase A family, 5; angiogenin; RNASE5; RNase 5; ribonuclease 5; epididymis luminal protein 168; ALS9; HEL168; RNASE4; MGC22466; MGC71966
• Gene ID: 283
• mRNA Refseq: NM_001145
• Protein Refseq: NP_001136
• MIM: 105850
• UniProt ID: P03950