Recombinant Human ANPEP Protein, C-His-tagged
Cat.No. : | ANPEP-053H |
Product Overview : | Recombinant Human ANPEP Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Aminopeptidase N (APN, CD13) is a widely expressed, membrane-bound proteolytic enzyme that breaks down peptides during digestion, cleaves cell surface antigens during antigen presentation, and acts as a receptor for human viruses, including several coronaviruses. This multifunctional protein is implicated in the regulation of many biological processes, including angiogenesis, cell proliferation, cell migration, inflammation and immune response. APN was originally identified as the cell surface antigen CD13, which is expressed in myeloid lineage hematopoietic cells and myeloid leukemia. Identified substrates of aminopeptidase N include the angiotensin I-III peptide hormones, the opioid peptide met-enkephalin, and cytokines MCP-1 and MIP-1. Abnormal APN protein expression is seen in various forms of cancer, with high APN expression associated with poor survival in colon cancer and non-small cell lung cancer and silenced APN expression related to poor prognosis in prostate cancer. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~40 kDa |
AA Sequence : | NDLFSTSGNEWVLLNLNVTGYYRVN YDEENWRKIQTQLQRDHSAIPVINR AQIINDAFNLASAHKVPVTLALNNT LFLIEERQYMPWEAALSSLSYFKLM FDRSEVYGPMKNYLKKQVTPLFIHF RNNTNNWREIPENLMDQYSEVNAIS TACSNGVPECEEMVSGLFKQWMENP NNNPIHPNLRSTVYCNAIAQGGEEE WDFAWEQFRNATLVNEADKLRAALA CSKELWILNRYLSYTLNPDLIRKQD ATSTIISITNNVIGQGLVWDFVQSN WKKLFNDYGGGSFSFSNLIQAVTRR FSTEYELQQLEQFKKDNEETGFGSG TRALEQALEKTKANIKWVKENKEVV LQWFTENSK |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -22 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | ANPEP alanyl (membrane) aminopeptidase [ Homo sapiens (human) ] |
Official Symbol : | ANPEP |
Synonyms : | ANPEP; alanyl (membrane) aminopeptidase; CD13, PEPN; aminopeptidase N; aminopeptidase M; gp150; LAP1; microsomal aminopeptidase; p150; AP-M; AP-N; hAPN; alanyl aminopeptidase; myeloid plasma membrane glycoprotein CD13; APN; CD13; P150; PEPN; GP150; |
Gene ID : | 290 |
mRNA Refseq : | NM_001150 |
Protein Refseq : | NP_001141 |
MIM : | 151530 |
UniProt ID : | P15144 |
Products Types
◆ Recombinant Protein | ||
ANPEP-2167H | Recombinant Human ANPEP Protein, MYC/DDK-tagged | +Inquiry |
Anpep-1294M | Recombinant Mouse Anpep Protein, MYC/DDK-tagged | +Inquiry |
ANPEP-2621P | Recombinant Pig ANPEP Protein (616-963 aa), His-Myc-tagged | +Inquiry |
ANPEP-159H | Recombinant Human ANPEP Protein, His-tagged | +Inquiry |
ANPEP-2657H | Recombinant Human ANPEP protein(151-230 aa), C-His-tagged | +Inquiry |
◆ Native Protein | ||
ANPEP-621H | Active Native Human ANPEP protein | +Inquiry |
◆ Lysates | ||
ANPEP-3090HCL | Recombinant Human ANPEP cell lysate | +Inquiry |
ANPEP-3000MCL | Recombinant Mouse ANPEP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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