Recombinant Human ANTXR1 Protein, MYC/DDK-tagged

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Recombinant Human ANTXR1 Protein, MYC/DDK-tagged

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Cat.No. : ANTXR1-2158H
Product Overview : Recombinant human ANTXR1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 34.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ANTXR1 anthrax toxin receptor 1 [ Homo sapiens ]
Official Symbol : ANTXR1
Synonyms : ATR; GAPO; TEM8
Gene ID : 84168
mRNA Refseq : NM_018153
Protein Refseq : NP_060623
MIM : 606410
UniProt ID : Q9H6X2

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