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Recombinant Human APEX1 protein, GST-tagged

Cat.No. : APEX1-45H
Product Overview : Recombinant Human APEX1 protein, fused with N-terminal GST tag was expressed in E.coli.
Source : E.coli
Species : Human
Tag : GST
Form : 50 mM Tris HCl, pH 8.0, 300 mM NaCl, 1 mM EDTA, 1 mM TCEP, 20% glycerol (w/v)
Molecular Mass : 62.5 kDa
Protein length : 1-318
Storage : Store at -70centigrade. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.
Gene Name : APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 [ Homo sapiens ]
Official Symbol : APEX1
Synonyms : APEX1; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX, APEX nuclease (multifunctional DNA repair enzyme); DNA-(apurinic or apyrimidinic site) lyase; APE; APE 1; APEN; APX; HAP1; REF 1; REF1; AP lyase; protein REF-1; redox factor-1; AP endonuclease class I; apurinic-apyrimidinic endonuclease 1; apurinic/apyrimidinic (abasic) endonuclease; deoxyribonuclease (apurinic or apyrimidinic); APE1; APEX;
Gene ID : 328
mRNA Refseq : NM_001244249
Protein Refseq : NP_001231178
MIM : 107748
UniProt ID : P27695
Chromosome Location : 14q11.2
Pathway : BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function : 3-5 exonuclease activity; 3-5 exonuclease activity; DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; DNA-(apurinic or apyrimidinic site) lyase activity; RNA binding; chromatin DNA binding; damaged DNA binding; endodeoxyribonuclease activity; endonuclease activity; hydrolase activity; lyase activity; metal ion binding; oxidoreductase activity; phosphodiesterase I activity; phosphoric diester hydrolase activity; protein binding; ribonuclease H activity; site-specific endodeoxyribonuclease activity, specific for altered base; transcription coactivator activity; transcription corepressor activity; uracil DNA N-glycosylase activity;

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