Recombinant Human ARHGAP24 Protein, His-tagged

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Recombinant Human ARHGAP24 Protein, His-tagged

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Cat.No. : ARHGAP24-2581H
Product Overview : Recombinant Human ARHGAP24 protein, fused to His-tagged at N-terminus, was expressed in E. coli.
Description : This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 73.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ARHGAP24 Rho GTPase activating protein 24 [ Homo sapiens ]
Official Symbol : ARHGAP24
Synonyms : FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
Gene ID : 83478
mRNA Refseq : NM_001025616
Protein Refseq : NP_001020787
MIM : 610586
UniProt ID : Q8N264

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