| Description : |
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
84.7 kDa |
| AA Sequence : |
MSGRSVRLRSVPIQSLSELERARLQ EVAFYQLQQDCDLSCQITIPKDGQK RKKSLRKKLDSLGKEKNKDKEFIPQ AFGMPLSQVIANDRAYKLKQDLQRD EQKDASDFVASLLPFGNKRQNKELS SSNSSLSSTSETPNESTSPNTPEPA PRARRRGAMSVDSITDLDDNQSRLL EALQLSLPAEAQSKKEKARDKKLSL NPIYRQVPRLVDSCCQHLEKHGLQT VGIFRVGSSKKRVRQLREEFDRGID VSLEEEHSVHDVAALLKEFLRDMPD PLLTRELYTAFINTLLLEPEEQLGT LQLLIYLLPPCNCDTLHRLLQFLSI VARHADDNISKDGQEVTGNKMTSLN LATIFGPNLLHKQKSSDKEFSVQSS ARAEESTAIIAVVQKMIENYEALFM VPPDLQNEVLISLLETDPDVVDYLL RRKASQSSSPDMLQSEVSFSVGGRH SSTDSNKASSGDISPYDNNSPVLSE RSLLAMQEDAAPGGSEKLYRVPGQF MLVGHLSSSKSRESSPGPRLGKDLS EEPFDIWGTWHSTLKSGSKDPGMTG SSGDIFESSSLRAGPCSLSQGNLSP NWPRWQGSPAELDSDTQGARRTQAA APATEGRAHPAVSRACSTPHVQVAG KAERPTARSEQYLTLSGAHDLSESE LDVAGLQSRATPQCQRPHGSGRDDK RPPPPYPGPGKPAAAAAWIQGPPEG VETPTDQGGQAAEREQQVTQKKLSS ANSLPAGEQDSPRLGDAGWLDWQRE RWQIWELLSTDNPDALPETLVTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
