Recombinant Human ARHGEF1 protein, GST-tagged ARHGEF1-777H

Recombinant Human ARHGEF1 protein, GST-tagged

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Recombinant Human ARHGEF1 protein, GST-tagged

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Cat.No. : ARHGEF1-777H
Product Overview : Human ARHGEF1 full-length ORF ( NP_004697.2, 1 a.a. - 912 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 128.8 kDa
AA Sequence : MEDFARGAASPGPSR PGLVPVSIIGAEDED FENELETNSEEQNSQ FQSLEQVKRRPAHLM ALLQHVALQFEPGPL LCCLHADMLGSLGPK EAKKAFLDFYHSFLE KTAVLRVPVPPNVAF ELDRTRADLISEDVQ RRFVQEVVQSQQVAV GRQLEDFRSKRLMGM TPWEQELAQLEAWVG RDRASYEARERHVAE RLLMHLEEMQHTIST DEEKSAAVVNAIGLY MRHLGVRTKSGDKKS GRNFFRKKVMGNRRS DEPAKTKKGLSSILD AARWNRGEPQVPDFR HLKAEVDAEKPGATD RKGGVGMPSRDRNIG APGQDTPGVSLHPLS LDSPDREPGADAPLE LGDSSPQGPMSLESL APPESTDEGAETESP EPGDEGEPGRSGLEL EPEEPPGWRELVPPD TLHSLPKSQVKRQEV ISELLVTEAAHVRML RVLHDLFFQPMAECL FFPLEELQNIFPSLD ELIEVHSLFLDRLMK RRQESGYLIEEIGDV LLARFDGAEGSWFQK ISSRFCSRQSFALEQ LKAKQRKDPRFCAFV QEAESRPRCRRLQLK DMIPTEMQRLTKYPL LLQSIGQNTEEPTER EKVELAAECCREILH HVNQAVRDMEDLLRL KDYQRRLDLSHLRQS SDPMLSEFKNLDITK KKLVHEGPLTWRVTK DKAVEVHVLLLDDLL LLLQRQDERLLLKSH SRTLTPTPDGKTMLR PVLRLTSAMTREVAT DHKAFYVLFTWDQEA QIYELVAQTVSERKN WCALITETAGSLKVP APASRPKPRPSPSST REPLLSSSENGNGGR ETSPADARTERILSD LLPFCRPGPEGQLAA TALRKVLSLKQLLFP AEEDNGAGPPRDGDG VPGGGPLSPARTQEI QENLLSLEETMKQLE ELEEEFCRLRPLLSQ LGGNSVPQPGCT
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 [ Homo sapiens ]
Official Symbol : ARHGEF1
Synonyms : ARHGEF1; Rho guanine nucleotide exchange factor (GEF) 1; rho guanine nucleotide exchange factor 1; LBCL2; P115 RHOGEF; SUB1.5; p115RhoGEF; Lsc homolog; 115-kD protein; 115 kDa guanine nucleotide exchange factor; LSC; GEF1; P115-RHOGEF;
Gene ID : 9138
mRNA Refseq : NM_004706
Protein Refseq : NP_004697
MIM : 601855
UniProt ID : Q92888

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