Recombinant Human ARHGEF1 protein, GST-tagged

• Cat.No.: ARHGEF1-777H
• Product Overview: Human ARHGEF1 full-length ORF ( NP_004697.2, 1 a.a. - 912 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 128.8 kDa
• AA Sequence: MEDFARGAASPGPSRPGLVPVSIIG AEDEDFENELETNSEEQNSQFQSLE QVKRRPAHLMALLQHVALQFEPGPL LCCLHADMLGSLGPKEAKKAFLDFY HSFLEKTAVLRVPVPPNVAFELDRT RADLISEDVQRRFVQEVVQSQQVAV GRQLEDFRSKRLMGMTPWEQELAQL EAWVGRDRASYEARERHVAERLLMH LEEMQHTISTDEEKSAAVVNAIGLY MRHLGVRTKSGDKKSGRNFFRKKVM GNRRSDEPAKTKKGLSSILDAARWN RGEPQVPDFRHLKAEVDAEKPGATD RKGGVGMPSRDRNIGAPGQDTPGVS LHPLSLDSPDREPGADAPLELGDSS PQGPMSLESLAPPESTDEGAETESP EPGDEGEPGRSGLELEPEEPPGWRE LVPPDTLHSLPKSQVKRQEVISELL VTEAAHVRMLRVLHDLFFQPMAECL FFPLEELQNIFPSLDELIEVHSLFL DRLMKRRQESGYLIEEIGDVLLARF DGAEGSWFQKISSRFCSRQSFALEQ LKAKQRKDPRFCAFVQEAESRPRCR RLQLKDMIPTEMQRLTKYPLLLQSI GQNTEEPTEREKVELAAECCREILH HVNQAVRDMEDLLRLKDYQRRLDLS HLRQSSDPMLSEFKNLDITKKKLVH EGPLTWRVTKDKAVEVHVLLLDDLL LLLQRQDERLLLKSHSRTLTPTPDG KTMLRPVLRLTSAMTREVATDHKAF YVLFTWDQEAQIYELVAQTVSERKN WCALITETAGSLKVPAPASRPKPRP SPSSTREPLLSSSENGNGGRETSPA DARTERILSDLLPFCRPGPEGQLAA TALRKVLSLKQLLFPAEEDNGAGPP RDGDGVPGGGPLSPARTQEIQENLL SLEETMKQLEELEEEFCRLRPLLSQ LGGNSVPQPGCT
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 [ Homo sapiens ]
• Official Symbol: ARHGEF1
• Synonyms: ARHGEF1; Rho guanine nucleotide exchange factor (GEF) 1; rho guanine nucleotide exchange factor 1; LBCL2; P115 RHOGEF; SUB1.5; p115RhoGEF; Lsc homolog; 115-kD protein; 115 kDa guanine nucleotide exchange factor; LSC; GEF1; P115-RHOGEF
• Gene ID: 9138
• mRNA Refseq: NM_004706
• Protein Refseq: NP_004697
• MIM: 601855
• UniProt ID: Q92888