Recombinant Human ARHGEF11 Protein, MYC/DDK-tagged ARHGEF11-2697H

Recombinant Human ARHGEF11 Protein, MYC/DDK-tagged


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Recombinant Human ARHGEF11 Protein, MYC/DDK-tagged

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Cat.No. : ARHGEF11-2697H
Product Overview : Recombinant Human ARHGEF11 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 172.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 [ Homo sapiens ]
Official Symbol : ARHGEF11
Synonyms : GTRAP48; PDZ-RHOGEF
Gene ID : 9826
mRNA Refseq : NM_014784
Protein Refseq : NP_055599
MIM : 605708
UniProt ID : O15085

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