Recombinant Human ARHGEF9 protein, GST-tagged

• Cat.No.: ARHGEF9-791H
• Product Overview: Human ARHGEF9 full-length ORF ( ADR83209.1, 1 a.a. - 516 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 56.8 kDa
• AA Sequence: MTLLITGDSIVSAEAVWDHVTMANR ELAFKAGDVIKVLDASNKDWWWGQI DDEEGWFPASFVRLWVNQEDEVEEG PSDVQNGHLDPNSDCLCLGRPLQNR DQMRANVINEIMSTERHYIKHLKDI CEGYLKQCRKRRDMFSDEQLKVIFG NIEDIYRFQMGFVRDLEKQYNNDDP HLSEIGPCFLEHQDGFWIYSEYCNN HLDACMELSKLMKDSRYQHFFEACR LLQQMIDIAIDGFLLTPVQKICKYP LQLAELLKYTAQDHSDYRYVAAALA VMRNVTQQINERKRRLENIDKIAQW QASVLDWEGEDILDRSSELIYTGEM AWIYQPYGRNQQRVFFLFDHQMVLC KKDLIRRDILYYKGRIDMDKYEVVD IEDGRDDDFNVSMKNAFKLHNKETE EIHLFFAKKLEEKIRWLRAFREERK MVQEDEKIGFEISENQKRQAAMTVR KVPKQKGVNSARSVPPSYPPPQDPL NHGQYLVPDGIAQSQVFEFTEPKRS QSPFWQNFSRLTPFKK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 [ Homo sapiens ]
• Official Symbol: ARHGEF9
• Synonyms: ARHGEF9; Cdc42 guanine nucleotide exchange factor (GEF) 9; rho guanine nucleotide exchange factor 9; collybistin; KIAA0424; PEM 2; PEM-2 homolog; hPEM-2 collybistin; rac/Cdc42 guanine nucleotide exchange factor 9; PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN
• Gene ID: 23229
• mRNA Refseq: NM_001173479
• Protein Refseq: NP_001166950
• MIM: 300429
• UniProt ID: O43307