Recombinant Human ARID4A, His-tagged

• Cat.No.: ARID4A-3680H
• Product Overview: AT-rich interactive domain-containing protein 4A (ARID4A), partial

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 1257
• Description: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ARID4A recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ARID4A AT rich interactive domain 4A (RBP1-like) [ Homo sapiens ]
• Official Symbol: ARID4A
• Synonyms: ARID4A; AT rich interactive domain 4A (RBP1-like); RBBP1, retinoblastoma binding protein 1; AT-rich interactive domain-containing protein 4A; RBP 1; RBP1; retinoblastoma binding protein 1; retinoblastoma-binding protein 1; ARID domain-containing protein 4A; RBBP1; RBP-1; RBBP-1
• Gene ID: 5926
• mRNA Refseq: NM_002892
• Protein Refseq: NP_002883
• MIM: 180201
• UniProt ID: P29374
• Chromosome Location: 14q22.3
• Function: DNA binding; sequence-specific DNA binding transcription factor activity