"ASCL1" Related Products

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Recombinant Human ASCL1 protein, His-tagged

Cat.No.: ASCL1-22H
Product Overview: Recombinant Human ASCL1, fused with N-His, was expressed in E. coli.
Description: Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5"-CANNTG-3").
Source: E.coli
Species: Human
Tag: His
Form: 20mM Tris.Cl, 100mM NaCl, 50% Glycerol, pH8.0.
Molecular Mass: 27.4kDa(including fusion tag)
Protein length: 251aa(including fusion tag)
Applications: WB, ELISA, IP, antibody production, protein array
Storage: Store at -80°C and avoid repeated freeze-thaw cycles.
Gene Name: ASCL1 achaete-scute complex homolog 1 (Drosophila) [ Homo sapiens ]
Official Symbol: ASCL1
Synonyms: ASCL1; ASH1; bHLHa46; HASH1; ASH-1; MASH1;
Gene ID: 429
mRNA Refseq: NM_004316
Protein Refseq: NP_004307
MIM: 100790
UniProt ID: P50553
Chromosome Location: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
Pathway: DNA binding; E-box binding; bHLH transcription factor binding; double-stranded DNA binding; protein binding; protein homodimerization activity; sequence-specific DNA binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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