Recombinant Human ATP1A2, His-tagged
Cat.No. : | ATP1A2-10005H |
Product Overview : | Recombinant Human ATP1A2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 347-700a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide [ Homo sapiens ] |
Official Symbol : | ATP1A2 |
Synonyms : | ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide; ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide , MHP2, migraine, hemiplegic 2; sodium/potassium-transporting ATPase subunit alpha-2; FHM2; sodium-potassium ATPase; sodium pump subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; Na+/K+ ATPase, alpha-B polypeptide; Na+/K+ ATPase, alpha-A(+) catalytic polypeptide; sodium/potassium-transporting ATPase alpha-2 chain; MHP2; MGC59864; |
Gene ID : | 477 |
mRNA Refseq : | NM_000702 |
Protein Refseq : | NP_000693 |
MIM : | 182340 |
UniProt ID : | P50993 |
Chromosome Location : | 1q21-q23 |
Pathway : | Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; |
Function : | ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; cation-transporting ATPase activity; hydrolase activity; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; me |
Products Types
◆ Recombinant Protein | ||
ATP1A2-276R | Recombinant Rhesus Macaque ATP1A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A2-2516H | Recombinant Human ATP1A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A2-509R | Recombinant Rat ATP1A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A2-0550H | Recombinant Human ATP1A2 Protein (Lys347-Glu700), N-His-tagged | +Inquiry |
ATP1A2-447R | Recombinant Rhesus monkey ATP1A2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ATP1A2-8612HCL | Recombinant Human ATP1A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket