Recombinant Human ATP6V1B2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | ATP6V1B2-2300H |
| Product Overview : | ATP6V1B2 MS Standard C13 and N15-labeled recombinant protein (NP_001684) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 56.4 kDa |
| AA Sequence : | MALRAMRGIV NGAAPELPVP TGGPAVGAQE QALAVSRNYL SQPRLTYKTV SGVNGPLVIL DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE GTSGIDAKKT SCEFTGDILR TPVSEDMLGR VFNGSGKPID RGPVVLAEDF LDIMGQPINP QCRIYPEEMI RTGISAIDGM NSIARGQKIP IFSAAGLPHN EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET ARFFKSDFEE NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VGGRNGSITQ IPILTMPNDD ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR LMKSAIGEGM TRKDHADVSN QLYACYAIGK DVQAMKAVVG EEALTSDDLL YLEFLQKFER NFIAQGPYEN RTVFETLDIG WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK HTRTRPLEQK LISEEDLAAN DILDYKDDDD KV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | ATP6V1B2 ATPase H+ transporting V1 subunit B2 [ Homo sapiens (human) ] |
| Official Symbol : | ATP6V1B2 |
| Synonyms : | ATP6V1B2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; ATP6B2, ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58kD, isoform 2, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 2, VPP3; V-type proton ATPase subunit B, brain isoform; HO57; VATB; Vma2; V-ATPase B2 subunit; V-ATPase subunit B 2; vacuolar proton pump subunit B 2; H+ transporting two-sector ATPase; vacuolar H+-ATPase 56,000 subunit; endomembrane proton pump 58 kDa subunit; VPP3; ATP6B2; ATP6B1B2; |
| Gene ID : | 526 |
| mRNA Refseq : | NM_001693 |
| Protein Refseq : | NP_001684 |
| MIM : | 606939 |
| UniProt ID : | P21281 |
◆ Recombinant Protein
| Atp6v1b2-671M | Recombinant Mouse Atp6v1b2 Protein, MYC/DDK-tagged | +Inquiry |
| ATP6V1B2-9668Z | Recombinant Zebrafish ATP6V1B2 | +Inquiry |
| ATP6V1B2-5562C | Recombinant Chicken ATP6V1B2 | +Inquiry |
| ATP6V1B2-2160M | Recombinant Mouse ATP6V1B2 Protein | +Inquiry |
| ATP6V1B2-1002H | Recombinant Human ATP6V1B2 protein, GST-tagged | +Inquiry |
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◆ Lysates
| ATP6V1B2-8583HCL | Recombinant Human ATP6V1B2 293 Cell Lysate | +Inquiry |
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ATP5OATP6AP2ATP6V1E1ATP6V1G1ATP7AATP7BATP5DATP13A2ATP1A1ATP1B3ATP2A1ATP2A3ATP2B1ATP2C1ATP5EATP5G1ATP6AP1ATP6V0D1ATP6V1B2ATP6V1C2ATP6V1G2ATP6V1B1ATP6V1FATP5BATP11BATP1A3ATP1B2ATP2B4ATP4BATP5IATP5JATP6V1AATP6V1DATP6V1G3ATP8B1ATP6V0D2ATP8B4ATP9AATP1B1ATP6V1HATP8A2ATP5C1ATP10DATP11CATP12AATP13A3ATP13A4ATP1A2ATP1B4ATP5A1ATP5F1ATP5HATP5J2ATP6AP1LATP6V0A1ATP6V0A4ATP6V0BATP6V0CATP2B2ATP2B3ATP11AATP8A1ATP13A1Atp9bATP5G3ATP10BATP4AATP5G2ATP5LATP5SATP5L2ATP5SLATP2A2ATP6V1E2ATP6V0A2ATP1A4Atp5kAtp13a5ATP8B2ATP8B3Atp2c2Atp8b5Atp10aAtp6v0e2ATP6V0E1Atp6v0eAtp6v1c1
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