Recombinant Human BIRC3, GST-tagged
Cat.No. : | BIRC3-190H |
Product Overview : | Recombinant full-length human BIRC3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | BIRC3 or baculoviral IAP repeat containing 3 is a member of the IAP family of proteins. BIRC3 inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and thereby interfering with activation of ICE-like proteases. BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. BIRC3 is a potential oncogene which is overexpressed in multiple lung cancers with or without higher copy numbers. BIRC3 is a key regulator of NOD innate immunity signaling. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~105 kDa |
Purity : | >75% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ] |
Official Symbol : | BIRC3 |
Synonyms : | BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF49; TNFR2 TRAF signaling complex protein; IAP-1; IAP homolog C; RING finger protein 49; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; AIP1; API2; CIAP2; HAIP1; HIAP1; c-IAP2; |
Gene ID : | 330 |
mRNA Refseq : | NM_001165 |
Protein Refseq : | NP_001156 |
MIM : | 601721 |
UniProt ID : | Q13489 |
Chromosome Location : | 11q22 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Ceramide signaling pathway, organism-specific biosystem; |
Function : | metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
BIRC3-319H | Recombinant Human BIRC3 Protein, His-tagged | +Inquiry |
BIRC3-2544H | Recombinant Human BIRC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BIRC3-69H | Recombinant Human BIRC3 protein, GST/StrepII-tagged | +Inquiry |
BIRC3-70H | Recombinant Human BIRC3 protein, His/StrepII-tagged | +Inquiry |
BIRC3-2540H | Recombinant Human BIRC3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
BIRC3-8451HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
BIRC3-8450HCL | Recombinant Human BIRC3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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