"BIRC5" Related Products

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Recombinant Human BIRC5 protein, MYC/DDK-tagged

Cat.No.: BIRC5-325H
Product Overview: Recombinant Human BIRC5, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Source: HEK293
Species: Human
Tag: MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 16.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: BIRC5 baculoviral IAP repeat containing 5 [ Homo sapiens ]
Official Symbol: BIRC5
Synonyms: BIRC5; baculoviral IAP repeat containing 5; API4, apoptosis inhibitor 4 , baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing protein 5; EPR 1; survivin; survivin variant 3 alpha; apoptosis inhibitor 4; apoptosis inhibitor survivin; API4; EPR-1;
Gene ID: 332
mRNA Refseq: NM_001168
Protein Refseq: NP_001159
MIM: 603352
UniProt ID: O15392
Chromosome Location: 17q25.3
Pathway: Apoptosis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem;
Function: Ran GTPase binding; chaperone binding; cobalt ion binding; cofactor binding; cysteine-type endopeptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enzyme binding; identical protein binding; metal ion binding; microtubule binding; microtubule binding; peptidase inhibitor activity; protein binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; tubulin binding; zinc ion binding; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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