Recombinant Human BTLA protein, His-Avi-tagged

• Cat.No.: BTLA-518H
• Product Overview: Recombinant Human BTLA Protein is expressed from mammalian with a His and Avi Tag at the C-terminal. It contains Met1-Ser150.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: It contains Met1-Ser150.
• Description: B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 . BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The Protein has a calculated MW of 16.7kDa. As a result of glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE.
• Endotoxin: Less than 0.01EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: BTLA B and T lymphocyte associated [ Homo sapiens ]
• Official Symbol: BTLA
• Synonyms: CD272 antigen; CD272; B and T lymphocyte associated; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA1; FLJ16065; MGC129743
• Gene ID: 151888
• mRNA Refseq: NM_001085357
• Protein Refseq: NP_001078826
• MIM: 607925
• UniProt ID: Q7Z6A9