Recombinant Human CA10, Fc-His tagged

• Cat.No.: CA10-257H
• Product Overview: Recombinant Human CA10 (NP_001076002.1) (Met 1-Asn 300), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.

Specification

• Source: Human Cells
• Species: Human
• Tag: His&Fc
• Form: Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
• Molecular Mass: The recombinant human CARPX/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 526 amino acids and migrates as an approximately 63 kDa band in SDS-PAGE under reducing conditions as predicted.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CA10 carbonic anhydrase X [ Homo sapiens ]
• Official Symbol: CA10
• Gene ID: 56934
• mRNA Refseq: NM_001082533
• Protein Refseq: NP_001076002
• MIM: 604642
• UniProt ID: Q9NS85

Reviews

08/26/2022

Accurate protein characterization, facilitates data interpretation.

08/05/2021

Dependable quantification, ensures data accuracy.

11/03/2020

Expert support, indispensable for our protein experiments.

Q&As

What is the tissue-specific expression pattern of CA10 protein?

CA10 protein is primarily expressed in the kidneys and brain.

What is the role of CA10 protein in intracellular pH regulation?

CA10 protein contributes to intracellular pH regulation.

How does CA10 protein's enzymatic activity compare to other carbonic anhydrases?

CA10 protein's enzymatic activity varies compared to other carbonic anhydrases, and further research is needed to identify its specific substrates and catalytic mechanisms.

Can genetic models be developed to study CA10 protein's cellular roles?

Yes, genetic models like knockouts can be developed to study CA10 protein's cellular functions and associated phenotypic changes.

What are the primary tissues expressing CA10 protein?

CA10 protein is primarily expressed in the kidneys and brain.

What post-translational modifications regulate CA10 protein's activity and stability?

The specific post-translational modifications governing CA10 protein's activity and stability are under investigation.

Are there known disease associations with CA10 protein?

There are currently no widely reported disease associations or implications related to CA10 protein.