Recombinant Human CA5A Protein, GST-Tagged
Cat.No. : | CA5A-0242H |
Product Overview : | Human CA5A full-length ORF (NP_001730.1, 1 a.a. - 305 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 61.2 kDa |
AA Sequence : | MLGRNTWKTSAFSFLVEQMWAPLWS RSMRPGRWCSQRSCAWQTSNNTLHP LWTVPVSVPGGTRQSPINIQWRDSV YDPQLKPLRVSYEAASCLYIWNTGY LFQVEFDDATEASGISGGPLENHYR LKQFHFHWGAVNEGGSEHTVDGHAY PAELHLVHWNSVKYQNYKEAVVGEN GLAVIGVFLKLGAHHQTLQRLVDIL PEIKHKDARAAMRPFDPSTLLPTCW DYWTYAGSLTTPPLTESVTWIIQKE PVEVAPSQLSAFRTLLFSALGEEEK MMVNNYRPLQPLMNRKVWASFQATN EGTRS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CA5A carbonic anhydrase VA, mitochondrial [ Homo sapiens ] |
Official Symbol : | CA5A |
Synonyms : | CA5A; carbonic anhydrase VA, mitochondrial; CA5; carbonic anhydrase 5A, mitochondrial; CAV; CAVA; CA-VA; carbonic dehydratase; carbonate dehydratase VA; carbonic anhydrase V, mitochondrial; |
Gene ID : | 763 |
mRNA Refseq : | NM_001739 |
Protein Refseq : | NP_001730 |
MIM : | 114761 |
UniProt ID : | P35218 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionPost-translational modifications of CA5A can be identified using mass spectrometry, with potential phosphorylation or acetylation sites.
Dysregulation of CA5A might influence metabolic processes in the liver, potentially impacting conditions like fatty liver disease or other metabolic disorders.
Specific mutations might affect CA5A's stability or activity, necessitating functional assays for validation.
While general carbonic anhydrase inhibitors might affect CA5A, specific modulators would need further research.
CA5A facilitates the reversible conversion of CO2 to bicarbonate and protons, playing a role in pH regulation and CO2 transport.
CA5A's activity is tailored to its mitochondrial environment, which might differ in kinetics from cytosolic isoforms.
CA5A is primarily expressed in the mitochondria of liver cells, with lesser amounts in other tissues.
Customer Reviews (3)
Write a reviewEfficient protein quantification, saves time and resources.
Consistency in results, a symbol of their service quality.
Top-tier protein sequencing, propels our research forward.
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