Recombinant Human CA9 protein, His-Avi-tagged

• Cat.No.: CA9-790H
• Product Overview: Recombinant Human Carbonic Anhydrase IX/CA9 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Gln 38-Asp 414.

Specification

• Description: CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in 50mM Tris,150mM NaCl PH 7.5.
• Molecular Mass: The protein has a predicted MW of 43.7 kDa.Due to glycosylation, the protein migrates to 50-60 KDa based on Bis-Tris PAGE result.
• Protein length: Gln 38-Asp 414
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles

Gene Information

• Gene Name: CA9 carbonic anhydrase 9 [Homo sapiens (human)]
• Official Symbol: CA9
• Synonyms: CA9; CAIX; CA-IX; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic Anhydrase IX; carbonic dehydratase; EC 4.2.1.1; G250; Membrane antigen MN; MN; P54/58N; PMW1; RCC; RCC-associated antigen G250; RCC-associated protein G250; Renal cell carcinoma-associated antigen G250
• Gene ID: 768
• mRNA Refseq: NM_001216.3
• Protein Refseq: NP_001207.2
• MIM: 603179
• UniProt ID: Q16790