Recombinant Human CACNA1S protein, His & T7-tagged

• Cat.No.: CACNA1S-1715H
• Product Overview: Recombinant Human CACNA1S aa. (Ala1657~Leu1873 (Accession # Q13698)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Ala1657~Leu1873
• Description: This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.8kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 6.2

Gene Information

• Gene Name: CACNA1S calcium voltage-gated channel subunit alpha1 S [ Homo sapiens (human) ]
• Official Symbol: CACNA1S
• Synonyms: CACNA1S; calcium voltage-gated channel subunit alpha1 S; MHS5; HOKPP; TTPP1; Cav1.1; HOKPP1; hypoPP; CCHL1A3; CACNL1A3; voltage-dependent L-type calcium channel subunit alpha-1S; calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis); calcium channel, voltage-dependent, L type, alpha 1S subunit; dihydropyridine receptor alpha 1 subunit; dihydropyridine-sensitive L-type calcium channel alpha-1 subunit; voltage-gated calcium channel subunit alpha Cav1.1
• Gene ID: 779
• mRNA Refseq: NM_000069.2
• Protein Refseq: NP_000060.2
• UniProt ID: Q13698