Recombinant Human CADPS, GST-tagged

• Cat.No.: CADPS-10654H
• Product Overview: Recombinant Human CADPS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-222a.a.
• Description: This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CADPS Ca++-dependent secretion activator [ Homo sapiens ]
• Official Symbol: CADPS
• Synonyms: Ca++-dependent secretion activator; CADPS1; CAPS; Ca2+-dependent activator protein for secretion; CAPS1; Ca2+-dependent secretion activator; KIAA1121; Ca2+-regulated cytoskeletal protein; Calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1; CAPS-1
• Gene ID: 8618
• mRNA Refseq: NM_183394.2
• Protein Refseq: NP_899631.1
• MIM: 604667
• UniProt ID: Q9ULU8
• Chromosome Location: 3p14.2
• Function: calcium ion binding;phospholipid binding;protein binding