Recombinant Human Cancer/Testis Antigen 1B

• Cat.No.: CTAG1B-1512H
• Product Overview: Recombinant human full length NY-ESO-1 protein was expressed inE. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO- 1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted to germ cells, particularly in the spermatogonia.
• Suggetsed Applications: ELISA, Inhibition Assays, Western Blotting. The optimal dilution for a specific application should be determined by the investigator.
• Supplied As: GST-NY-ESO-1 fusion protein was purified from E.coli and packaged at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 49kDa including GST.
• Storage And Stability: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
• Full Length: Full L.

Gene Information

• Gene Name: CTAG1B cancer/testis antigen 1B [ Homo sapiens ]
• Synonyms: CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1; cancer antigen 3; New York esophageal squamous cell carcinoma 1; LAGE2A; Cancer/testis antigen 1; L antigen family member 2; Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 6.1
• Gene ID: 1485
• mRNA Refseq: NM_001327
• Protein Refseq: NP_001318
• UniProt ID: P78358
• Chromosome Location: Xq28
• MIM: 300156

Citation

Aptamer-Containing Surfaces for Selective Capture of CD4 Expressing Cells

Journal: Langmuir : the ACS journal of surfaces and colloids    PubMed ID: 22856558    Data: 2012/8/14

Authors: Qing Zhou, Ying Liu, Alexander Revzin

Article Snippet:Anti-human CD4 antibody was purchased from BD Biosciences (San Diego, CA).Anti-human CD4 antibody was purchased from BD Biosciences (San Diego, CA).. Recombinant CD4 and CD8 antigen were purchased from Creative BioMart (Shirley, NY). . CellTracker Green CMFDA (5-chloromethylfluorescein diacetate) and CellTracker Red CMTPX were purchased from Invitrogen(where located).CellTracker Green CMFDA (5-chloromethylfluorescein diacetate) and CellTracker Red CMTPX were purchased from Invitrogen(where located).