Recombinant Human Casein Beta, His-tagged

• Cat.No.: CSN2-5541H
• Product Overview: Recombinant human CSN2protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Species: Human
• Tag: His
• Description: CSN2,also known as beta-casein precursor, belongs to the beta-casein family. CSN2has important role in determination of the surface properties of the caseinmicelles.
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol, 0.5M NaCl, 0.25M imidazole,1mM DTT, 0.1mM PMSF.
• Molecular Weight: 26.6 kDa(236aa) confirmed by MALDI-TOF
• Purity: > 95%by SDS-PAGE
• Concentration: 0.25mg/ml (determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMRETIE SLSSSEESIT EYKQKVEKVK HEDQQQGEDE HQDKIYPSFQ PQPLIYPFVEPIPYGFLPQN ILPLAQPAVV LPVPQPEIME VPKAKDTVYT KGRVMPVLKS PTIPFFDPQI PKLTDLENLHLPLPLLQPLM QQVPQPIPQT LALPPQPLWS VPQPKVLPIP QQVVPYPQRA VPVQALLLNQ ELLLNPTHQIYPVTQPLAPV HNPISV
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Glucocorticoidreceptor regulatory network; Signaling events mediated by PTP1B

Gene Information

• Gene Name: CSN2 casein beta [ Homosapiens ]
• Official Symbol: CSN2
• Synonyms: CSN2; casein beta; CASB; beta-casein
• Gene ID: 1447
• mRNA Refseq: NM_001891
• Protein Refseq: NP_001882
• MIM: 115460
• UniProt ID: P05814
• Chromosome Location: 4q21.1
• Function: calcium ion binding; enzyme inhibitoractivity; transporter activity