Recombinant Human CASR Protein, His tagged
Cat.No. : | CASR-49H |
Product Overview : | Recombinant Human CASR Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Molecular Mass : | The protein has a calculated MW of 67 kDa. |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMYGPD QRAQKKGDIILGGLFPIHFGVAAKD QDLKSRPESVECIRYNFRGFRWLQA MIFAIEEINSSPALLPNLTLGYRIF DTCNTVSKALEATLSFVAQNKIDSL NLDEFCNCSEHIPSTIAVVGATGSG VSTAVANLLGLFYIPQVSYASSSRL LSNKNQFKSFLRTIPNDEHQATAMA DIIEYFRWNWVGTIAADDDYGRPGI EKFREEAEERDICIDFSELISQYSD EEEIQHVVEVIQNSTAKVIVVFSSG PDLEPLIKEIVRRNITGKIWLASEA WASSSLIAMPQYFHVVGGTIGFALK AGQIPGFREFLKKVHPRKSVHNGFA KEFWEETFNCHLQEGAKGPLPVDTF LRGHEESGDRFSNSSTAFRPLCTGD ENISSVETPYIDYTHLRISYNVYLA VYSIAHALQDIYTCLPGRGLFTNGS CADIKKVEAWQVLKHLRHLNFTNNM GEQVTFDECGDLVGNYSIINWHLSP EDGSIVFKEVGYYNVYAKKGERLFI NEEKILWSGFSREVPFSNCSRDCLA GTRKGIIEGEPTCCFECVECPDGEY SDETDASACNKCPDDFWSNENHTSC IAK |
Purity : | > 95% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.62 mg/mL |
Storage Buffer : | Sterile 20 mM Tris, 100 mM NaCl, 5 mM EDTA, pH 8.0 |
Gene Name : | CASR calcium-sensing receptor [ Homo sapiens ] |
Official Symbol : | CASR |
Synonyms : | CASR; calcium-sensing receptor; HHC, HHC1, hypocalciuric hypercalcemia 1; extracellular calcium-sensing receptor; FHH; GPRC2A; NSHPT; severe neonatal hyperparathyroidism; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor; CAR; FIH; HHC; EIG8; HHC1; PCAR1; MGC138441; |
Gene ID : | 846 |
mRNA Refseq : | NM_000388 |
Protein Refseq : | NP_000379 |
MIM : | 601199 |
UniProt ID : | P41180 |
Products Types
◆ Recombinant Protein | ||
CASR-0439H | Recombinant Human CASR Protein, GST-Tagged | +Inquiry |
CASR-806R | Recombinant Rat CASR Protein, His (Fc)-Avi-tagged | +Inquiry |
CASR-23H | Recombinant Human CASR Protein (Y20-S1078 end), N-HA/Flag and C-10×His-tagged | +Inquiry |
CASR-01H | Recombinant Human CASR Protein (Tyr20-Lys601), C-6×His-tagged | +Inquiry |
CASR-1349H | Recombinant Human CASR Protein (20-612 aa), His-tagged | +Inquiry |
◆ Lysates | ||
CASR-7825HCL | Recombinant Human CASR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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