Recombinant Human CBX5 Protein, MYC/DDK-tagged

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Recombinant Human CBX5 Protein, MYC/DDK-tagged

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Cat.No. : CBX5-32H
Product Overview : Recombinant protein of human chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 3 with a C-Myc/DDK tag was expressed in HEK293T.
Description : This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : HEK293T
Species : Human
Tag : Myc/DDK
Molecular Mass : 22 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Figure :

Gene Name : CBX5 chromobox 5 [ Homo sapiens (human) ]
Official Symbol : CBX5
Synonyms : CBX5; chromobox 5; HP1; HP1A; HEL25; chromobox protein homolog 5; HP1 alpha homolog; HP1-ALPHA; HP1Hs alpha; antigen p25; chromobox homolog 5 (HP1 alpha homolog, Drosophila); epididymis luminal protein 25; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha
Gene ID : 23468
mRNA Refseq : NM_012117
Protein Refseq : NP_036249
MIM : 604478
UniProt ID : P45973

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