Recombinant Human CBX5 Protein, MYC/DDK-tagged

• Cat.No.: CBX5-32H
• Product Overview: Recombinant protein of human chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 3 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: CBX5 chromobox 5 [ Homo sapiens (human) ]
• Official Symbol: CBX5
• Synonyms: CBX5; chromobox 5; HP1; HP1A; HEL25; chromobox protein homolog 5; HP1 alpha homolog; HP1-ALPHA; HP1Hs alpha; antigen p25; chromobox homolog 5 (HP1 alpha homolog, Drosophila); epididymis luminal protein 25; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha
• Gene ID: 23468
• mRNA Refseq: NM_012117
• Protein Refseq: NP_036249
• MIM: 604478
• UniProt ID: P45973