Recombinant Human CCDC50 Protein, GST-Tagged

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Recombinant Human CCDC50 Protein, GST-Tagged

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Cat.No. : CCDC50-0558H
Product Overview : Human CCDC50 full-length ORF (AAH65004.1, 1 a.a. - 306 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.06 kDa
AA Sequence : MAEVSIDQSK LPGVKEVCRD FAVLEDHTLA HSLQEQEIEH HLASNVQRNR LVQHDLQVAK QLQEEDLKAQ AQLQKRYKDL EQQDCEIAQE IQEKLAIEAE RRRIQEKKDE DIARLLQEKE LQEEKKRKKH FPEFPATRAY ADSYYYEDGG MKPRVMKEAV STPSRMAHRD QEWYDAEIAR KLQEEELLAT QVDMRAAQVA QDEEIARLLM AEEKKAYKKA KEREKSSLDK RKQDPEWKPK TAKAANSKSK ESDEPHHSKN ERPARPPPPI MTDGEDADYT HFTNQQSSTR HFSKSESSHK GFHYKH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CCDC50 coiled-coil domain containing 50 [ Homo sapiens ]
Official Symbol : CCDC50
Synonyms : CCDC50; coiled-coil domain containing 50; C3orf6, deafness, autosomal dominant 44, DFNA44; coiled-coil domain-containing protein 50; Ymer; protein Ymer; YMER; C3orf6; DFNA44;
Gene ID : 152137
mRNA Refseq : NM_174908
Protein Refseq : NP_777568
MIM : 611051
UniProt ID : Q8IVM0

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