Recombinant Human CCNE2 Protein, GST-Tagged

• Cat.No.: CCNE2-0667H
• Product Overview: Human CCNE2 full-length ORF (AAH20729, 1 a.a. - 374 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.88 kDa
• AA Sequence: MSRRSSRLQAKQQPQPSQTESPQEA QIIQAKKRKTTQDVKKRREEVTKKH QYEIRNCWPPVLSGGISPCIIIETP HKEIGTSDFSRFTNYRFKNLFINPS PLPDLSWGCSKEVWLNMLKKESRYV HDKHFEVLHSDLEPQMRSILLDWLL EVCEVYTLHRETFYLAQDFFDRFML TQKDINKNMLQLIGITSLFIASKLE EIYAPKLQEFAYVTDGACSEEDILR MELIILKALKWELCPVTIISWLNLF LQVDALKDAPKVLLPQYSQETFIQI AQLLDLCILAIDSLEFQYRILTAAA LCHFTSIEVVKKASGLEWDSISECV DWMVPFVNVVKSTSPVKLKTFKKIP MEDRHNIQTHTNYLAMLCMISSHV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCNE2 cyclin E2 [ Homo sapiens ]
• Official Symbol: CCNE2
• Synonyms: CCNE2; cyclin E2; G1/S-specific cyclin-E2; CYCE2
• Gene ID: 9134
• mRNA Refseq: NM_057749
• Protein Refseq: NP_477097
• MIM: 603775
• UniProt ID: O96020