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Recombinant Human CD177 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CD177-4896H
Product Overview : CD177 MS Standard C13 and N15-labeled recombinant protein (NP_065139) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 46.4 kDa
AA Sequence : MSPVLLLALLGFILPLPGVQALLCQ FGTVQHVWKVSDLPRQWTPKNTSCD SGLGCQDTLMLIESGPQVSLVLSKG CTEAKDQEPRVTEHRMGPGLSLISY TFVCRQEDFCNNLVNSLPLWAPQPP ADPGSLRCPVCLSMEGCLEGTTEEI CPKGTTHCYDGLLRLRGGGIFSNLR VQGCMPQPGCNLLNGTQEIGPVGMT ENCNRKDFLTCHRGTTIMTHGNLAQ EPTDWTTSNTEMCEVGQVCQETLLL LDVGLTSTLVGTKGCSTVGAQNSQK TTIHSAPPGVLVASYTHFCSSDLCN SASSSSVLLNSLPPQAAPVPGDRQC PTCVQPLGTCSSGSPRMTCPRGTTH CYDGYIHLSGGGLSTKMSIQGCVAQ PSSFLLNHTRQIGIFSAREKRDVQP PASQHEGGGAEGLESLTWGVGLALA PALWWGVVCPSCTRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CD177 CD177 molecule [ Homo sapiens (human) ]
Official Symbol : CD177
Synonyms : CD177; CD177 molecule; CD177 antigen; HNA2A; NB1; polycythemia rubra vera 1; PRV1; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; PRV-1; HNA-2a; NB1 GP;
Gene ID : 57126
mRNA Refseq : NM_020406
Protein Refseq : NP_065139
MIM : 162860
UniProt ID : Q8N6Q3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (4)

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What is the relationship between CD177 expression and E⁃calmodulin expression in tumor tissue? 10/11/2023

In tumor tissues, CD177 expression was negatively correlated with E-calmodulin expression.

Where is CD177 primarily expressed? 08/12/2022

CD177 is predominantly expressed in neutrophils.

Where is CD177 located? 07/20/2022

CD177 is localized to the cell membrane.

What diseases is CD177 involved in? 01/03/2021

CD177 is involved in ovarian, colon and pancreatic cancer.

Customer Reviews (3)

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Reviews
10/19/2022

    CD177 proteins purchased are as advertised and the quality of the product is guaranteed.

    01/25/2022

      The company provides one-stop service, from the purchase of products to the completion of experiments in one go.

      03/08/2021

        Customer service was patient, prompt and accurate in answering my queries.

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