Recombinant Human CD177 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CD177-4896H |
Product Overview : | CD177 MS Standard C13 and N15-labeled recombinant protein (NP_065139) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 46.4 kDa |
AA Sequence : | MSPVLLLALLGFILPLPGVQALLCQ FGTVQHVWKVSDLPRQWTPKNTSCD SGLGCQDTLMLIESGPQVSLVLSKG CTEAKDQEPRVTEHRMGPGLSLISY TFVCRQEDFCNNLVNSLPLWAPQPP ADPGSLRCPVCLSMEGCLEGTTEEI CPKGTTHCYDGLLRLRGGGIFSNLR VQGCMPQPGCNLLNGTQEIGPVGMT ENCNRKDFLTCHRGTTIMTHGNLAQ EPTDWTTSNTEMCEVGQVCQETLLL LDVGLTSTLVGTKGCSTVGAQNSQK TTIHSAPPGVLVASYTHFCSSDLCN SASSSSVLLNSLPPQAAPVPGDRQC PTCVQPLGTCSSGSPRMTCPRGTTH CYDGYIHLSGGGLSTKMSIQGCVAQ PSSFLLNHTRQIGIFSAREKRDVQP PASQHEGGGAEGLESLTWGVGLALA PALWWGVVCPSCTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CD177 CD177 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD177 |
Synonyms : | CD177; CD177 molecule; CD177 antigen; HNA2A; NB1; polycythemia rubra vera 1; PRV1; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; PRV-1; HNA-2a; NB1 GP; |
Gene ID : | 57126 |
mRNA Refseq : | NM_020406 |
Protein Refseq : | NP_065139 |
MIM : | 162860 |
UniProt ID : | Q8N6Q3 |
Products Types
◆ Recombinant Protein | ||
CD177-1437M | Recombinant Mouse CD177 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD177-0730H | Recombinant Human CD177 Protein, GST-Tagged | +Inquiry |
CD177-126H | Recombinant Human CD177 Protein, His-tagged | +Inquiry |
CD177-533H | Recombinant Human CD177 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD177-3041H | Recombinant Human CD177 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CD177-778HCL | Recombinant Human CD177 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionIn tumor tissues, CD177 expression was negatively correlated with E-calmodulin expression.
CD177 is predominantly expressed in neutrophils.
CD177 is localized to the cell membrane.
CD177 is involved in ovarian, colon and pancreatic cancer.
Customer Reviews (3)
Write a reviewCD177 proteins purchased are as advertised and the quality of the product is guaranteed.
The company provides one-stop service, from the purchase of products to the completion of experiments in one go.
Customer service was patient, prompt and accurate in answering my queries.
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