Recombinant Human CD207 protein, His-tagged

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Recombinant Human CD207 protein, His-tagged

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Cat.No. : CD207-50H
Product Overview : Recombinant human CD207, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description : CD207, also known as C-type lectin domain family 4 member K, is a type 2 transmembrane glycoprotein. This protein is used as a marker for Langerhans cell which represent the immature dendritic cells in the epidermis. Also, it internalizes endogenous proteins such as type 1 procollagen. Internalization by Langerhans cell is thought to lead to suppression of self reactions. CD207 meditates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae.
Source : Insect cells
Species : Human
Tag : His tag
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 30.9kDa (273aa)28-40KDa (SDS–PAGE under reducing conditions.)
AA Sequence : ADPPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEPHHH HHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1.0mg/ml (determined by Absorbance at 280nm)
Gene Name : CD207 CD207 molecule, langerin [ Homo sapiens ]
Official Symbol : CD207
Synonyms : CD207; CD207 molecule, langerin; CD207 antigen, langerin; CLEC4K; Langerin
Gene ID : 50489
mRNA Refseq : NM_015717
Protein Refseq : NP_056532
MIM : 604862
UniProt ID : Q9UJ71
Chromosome Location : 2p13
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and presentation, organism-specific biosystem; Cross-presentation of soluble exogenous antigens (endosomes), organism-specific biosystem; Immune System, organism-specific biosystem;
Function : binding; mannose binding; sugar binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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