Recombinant Human CD207 Protein, His-tagged

• Cat.No.: CD207-108H
• Product Overview: Recombinant Human CD207 Protein with His tag was expressed in E. coli.

Specification

• Description: Langerin (CD207) is a C-type lectin receptor whose expression is restricted mainly to dendritic cells in the skin including Langerhans cells in the epidermis and langerin+/CD103+ dermal dendritic cells. Langerin is found on the cell surface and within rod-shaped organelles called Birbeck granules, and its expression is required for the formation of Birbeck granules. Langerin recognizes carbohydrate motifs on the surface of pathogens, resulting in endocytosis of the pathogen into Birbeck granules, degradation of the pathogen, and antigen presentation to T cells.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: ~35 kDa
• AA Sequence: PRFMGTISDVKTNVQLLKGRVDNIS TLDSEIKKNSDGMEAAGVQIQMVNE SLGYVRSQFLKLKTSVEKANAQIQI LTRSWEEVSTLNAQIPELKSDLEKA SALNTKIRALQGSLENMSKLLKRQN DILQVVSQGWKYFKGNFYYFSLIPK TWYSAEQFCVSRNSHLTSVTSESEQ EFLYKTAGGLIYWIGLTKAGMEGDW SWVDDTPFNKVQSVRFWIPGEPNNA GNNEHCGNIKAPSLQAWNDAPCDKT FLFICKRPYVPSEP
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: CD207 CD207 molecule, langerin [ Homo sapiens (human) ]
• Official Symbol: CD207
• Synonyms: CD207; CD207 molecule, langerin; CD207 antigen, langerin; C-type lectin domain family 4 member K; CLEC4K; Langerin; Langerhans cell specific c-type lectin; C-type lectin domain family 4, member K
• Gene ID: 50489
• mRNA Refseq: NM_015717
• Protein Refseq: NP_056532
• MIM: 604862
• UniProt ID: Q9UJ71