Active Recombinant Human CD22 Protein, Fc & Avi-tagged, Biotinylated
Cat.No. : | CD22-334H |
Product Overview : | Recombinant Human CD22 Protein, Fc & Avi-tagged, Biotinylated is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 687 (Accession # P20273-1). Predicted N-terminus: Asp 20. This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag. The protein has a calculated MW of 103.9 kDa. The protein migrates as 115-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. The biotin to protein ratio is 0.5-1 as determined by the HABA assay. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc & Avi |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Anti-Human CD22 MAb at 0.5 μg/mL (100 μL/well) can bind Recombinant Human CD22 Protein, Fc & Avi-tagged, Biotinylated with a linear range of 1-16 ng/mL (QC tested). |
Molecular Mass : | 103.9 kDa |
Protein length : | Asp 20 - Arg 687 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Notes : | Please avoid repeated freeze-thaw cycles. |
Stability : | No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | CD22 CD22 molecule [ Homo sapiens ] |
Official Symbol : | CD22 |
Synonyms : | CD22; CD22 molecule; CD22 antigen; B-cell receptor CD22; SIGLEC 2; SIGLEC2; BL-CAM; SIGLEC-2; FLJ22814; MGC130020; |
Gene ID : | 933 |
mRNA Refseq : | NM_001185099 |
Protein Refseq : | NP_001172028 |
MIM : | 107266 |
UniProt ID : | P20273 |
Products Types
◆ Recombinant Protein | ||
CD22-3947H | Active Recombinant Human CD22 Protein, His-tagged | +Inquiry |
CD22-533H | Recombinant Human CD22 Protein (Met1-Arg687) (ECD) | +Inquiry |
CD22-663H | Recombinant Human CD22 Protein, His-tagged | +Inquiry |
Cd22-535MB | Recombinant Mouse Cd22 Protein (Met1-Arg708), His tagged, Biotinylated | +Inquiry |
CD22-441H | Recombinant Human CD22 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD22-001MCL | Recombinant Mouse CD22 cell lysate | +Inquiry |
CD22-1956HCL | Recombinant Human CD22 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCD22-targeted immunotherapy is more targeted, specifically attacking cancer cells, whereas chemotherapy affects both healthy and cancerous cells.
Yes, CD22-targeted therapies are often used in combination with chemotherapy or other immunotherapies for enhanced efficacy.
CD22-targeted therapies are being explored for autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus.
Yes, CD22 is targeted in immunotherapy for B cell malignancies like acute lymphoblastic leukemia (ALL).
CD22 acts as an inhibitory receptor, regulating B cell activation and signaling.
Customer Reviews (3)
Write a reviewThe CD22 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.
Its unique properties make CD22 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.
With the CD22 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.
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