Recombinant Human CD40 Protein, His-tagged, FITC conjugated
Cat.No. : | CD40-2221HF |
Product Overview : | FITC conjugated recombinant human CD40 (Glu21-Arg193) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3). |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 21.1 kDa. The protein migrates as 29-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Glu21-Arg193 |
N-terminal Sequence Analysis : | Glu 21 |
Endotoxin : | < 1.0 EU/ μg by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | CD40 |
Official Symbol : | CD40 |
Synonyms : | CD40; CD40 molecule, TNF receptor superfamily member 5; TNFRSF5, tumor necrosis factor receptor superfamily, member 5; tumor necrosis factor receptor superfamily member 5; Bp50; p50; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily, member 5; nerve growth factor receptor-related B-lymphocyte activation molecule; CDW40; TNFRSF5; MGC9013 |
Gene ID : | 958 |
mRNA Refseq : | NM_001250 |
Protein Refseq : | NP_001241 |
MIM : | 109535 |
UniProt ID : | P25942 |
Products Types
◆ Recombinant Protein | ||
CD40-928C | Recombinant Canine CD40 Protein (Glu21-Ala194), His-tagged | +Inquiry |
CD40-32H | Recombinant Human CD40 Protein (ECD), His-tagged(C-ter) | +Inquiry |
CD40-630M | Recombinant Mouse CD40 Protein | +Inquiry |
CD40-679H | Recombinant Human CD40 Protein, His-tagged | +Inquiry |
CD40-31H | Recombinant Human CD40 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
CD40-001CCL | Recombinant Canine CD40 cell lysate | +Inquiry |
CD40-1831MCL | Recombinant Mouse CD40 cell lysate | +Inquiry |
CD40-2617HCL | Recombinant Human CD40 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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