Recombinant Human CD6 protein, His/T7-tagged

• Cat.No.: CD6-312H
• Product Overview: Recombinant Human CD6(18-402 aa) fused with His/T7 tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His/T7
• Form: Liquid
• Molecular Mass: 44 kDa
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFHPSPAPPDQLNTSSAESELWE PGERLPVRLTNGSSSCSGTVEVRLE ASWEPACGALWDSRAAEAVCRALGC GGAEAASQLAPPTPELPPPPAAGNT SVAANATLAGAPALLCSGAEWRLCE VVEHACRSDGRRARVTCAENRALRL VDGGGACAGRVEMLEHGEWGSVCDD TWDLEDAHVVCRQLGCGWAVQALPG LHFTPGRGPIHRDQVNCSGAEAYLW DCPGLPGQHYCGHKEDAGAVCSEHQ SWRLTGGADRCEGQVEVHFRGVWNT VCDSEWYPSEAKVLCQSLGCGTAVE RPKGLPHSLSGRMYYSCNGEELTLS NCSWRFNNSNLCSQSLAARVLCSAS RSLHNLSTPEVPASVQTVTIESSVT VKIENKESRELMLL
• Purity: >90% by SDS-PAGE.
• Applications: SDS-PAGE
• Concentration: 50 µg at 0.5 mg/ml
• Shipping: Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: CD6 CD6 molecule [ Homo sapiens ]
• Official Symbol: CD6
• Synonyms: CD6; CD6 molecule; CD6 antigen; T-cell differentiation antigen CD6; Tp120; T12; TP120; FLJ44171
• Gene ID: 923
• mRNA Refseq: NM_001254750
• Protein Refseq: NP_001241679
• MIM: 186720
• UniProt ID: P30203
• Chromosome Location: 11q12.2
• Pathway: Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
• Function: scavenger receptor activity