| Description : |
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
58.4 kDa |
| AA Sequence : |
MGRHVATSCHVAWLLVLISGCWGQV NRLPFFTNHFFDTYLLISEDTPVGS SVTQLLAQDMDNDPLVFGVSGEEAS RFFAVEPDTGVVWLRQPLDRETKSE FTVEFSVSDHQGVITRKVNIQVGDV NDNAPTFHNQPYSVRIPENTPVGTP IFIVNATDPDLGAGGSVLYSFQPPS QFFAIDSARGIVTVIRELDYETTQA YQLTVNATDQDKTRPLSTLANLAII ITDVQDMDPIFINLPYSTNIYEHSP PGTTVRIITAIDQDKGRPRGIGYTI VSGNTNSIFALDYISGVLTLNGLLD RENPLYSHGFILTVKGTELNDDRTP SDATVTTTFNILVIDINDNAPEFNS SEYSVAITELAQVGFALPLFIQVVD KDENLGLNSMFEVYLVGNNSHHFII SPTSVQGKADIRIRVAIPLDYETVD RYDFDLFANESVPDHVGYAKVKITL INENDNRPIFSQPLYNISLYENVTV GTSVLTVLVSPRFTAGPLSSPGPTV VRHPEGFCPRDLSNQGRRHPQIPEL CLLVYTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
