||Human CDK7 (NM_001799, 1 a.a. - 346a.a.) and CCNH (NM_001239, 1 a.a. - 323 a.a.) and MNAT1 (NM_002431, 1 a.a. a.a. - 309 a.a.) recombinant protein with GST-His tag expressed in Sf9 cells.
||The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
||22 pmol/μg x min
||CDK7: 68.934, CCNH: kDa
||Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing
||In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)