Recombinant Human CENPA Protein, GST-Tagged CENPA-1111H

Recombinant Human CENPA Protein, GST-Tagged

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Recombinant Human CENPA Protein, GST-Tagged

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Cat.No. : CENPA-1111H
Product Overview : Human CENPA full-length ORF (AAH00881, 1 a.a. - 114 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 38.28 kDa
AA Sequence : MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE IRKLQKSTHL LIRKLPFSRL AAEAFLVHLF EDAYLLTLHA GRVTLFPKDV QLARRIRGLE EGLG
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CENPA centromere protein A [ Homo sapiens ]
Official Symbol : CENPA
Synonyms : CENPA; centromere protein A; centromere protein A (17kD), centromere protein A, 17kDa; histone H3-like centromeric protein A; CenH3; CENP A; centromere specific histone; histone H3 like centromeric protein A; centromere autoantigen A; centromere protein A, 17kDa; centromere-specific histone; CENP-A;
Gene ID : 1058
mRNA Refseq : NM_001042426
Protein Refseq : NP_001035891
MIM : 117139
UniProt ID : P49450
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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