Recombinant Human CFL2 Protein, GST-Tagged CFL2-1174H

Recombinant Human CFL2 Protein, GST-Tagged

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Recombinant Human CFL2 Protein, GST-Tagged

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Cat.No. : CFL2-1174H
Product Overview : Human CFL2 full-length ORF (NP_068733.1, 1 a.a. - 166 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 45.1 kDa
AA Sequence : MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CFL2 cofilin 2 (muscle) [ Homo sapiens ]
Official Symbol : CFL2
Synonyms : CFL2; cofilin 2 (muscle); cofilin-2; cofilin, muscle isoform; NEM7;
Gene ID : 1073
mRNA Refseq : NM_001243645
Protein Refseq : NP_001230574
MIM : 601443
UniProt ID : Q9Y281

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