Recombinant Human Chemokine (C-C motif) Ligand 19, T7-tagged

• Cat.No.: CCL19-154H
• Product Overview: Recombinant human CCL19 protein, fused to T7-tag at N-terminus, was expressed inE.coliand purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.MW = 10.4 kDa (93aa).

Specification

• Description: CCL19 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein is involved in immunoregulatory and inflammatory processes. It elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells, CCR7+ effector-memory T-Cells.
• Source: E.coli.
• Form: Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MASMTGGQQM GRGSHMGTND AEDCCLSVTQ KPIPGYIVRN FHYLLIKDGC RVPAVVFTTL RGRQLCAPPD QPWVERIIQR LQRTSAKMKR RSS.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CCL19 chemokine (C-C motif) ligand 19 [ Homo sapiens ]
• Synonyms: small inducible cytokine A19; exodus-3; CK beta-11; EBI1-ligand chemokine ; CC chemokine ligand 19; beta chemokine exodus-3; small inducible cytokine subfamily A (Cys-Cys), member 19; ELC; CKb11; MIP3B; MIP-3b; SCYA19; MGC34433; CCL19; Macrophage inflammatory protein 3 beta; Short name=MIP-3-beta; EBI1-ligand chemokine;Short name=ELC; Beta chemokine exodus-3; CK beta-11; C-C motif chemokine 19; ELC; MIP3B; SCYA19; Chemokine (C-C motif) Ligand 19
• Gene ID: 6363
• mRNA Refseq: NM_006274
• Protein Refseq: NP_006265
• MIM: 602227
• UniProt ID: Q99731
• Chromosome Location: 9p13
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Signaling by GPCR
• Function: chemokine activity