Recombinant Human Ciliary Neurotrophic Factor, His-tagged
Cat.No. : | CNTF-08H |
Product Overview : | Recombinant human CNTF, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques(220 aa, 25 kDa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | CNTF-08H |
Description : | CNTF (Ciliary neurotrophic factor) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. This protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF protein is structurally related to leukemia inhibitory factor (LIF), interleukin-6 (IL-6), interleukin-11 (IL-11) and oncostatin M (OSM). It is localized in the cell nucleus subsequent to receptor binding. |
Source : | Escherichia Coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT. |
Molecular Weight : | 25 kDa (220 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Amino acid sequence : | MGSSHHHHHH SSGLVPRGSH MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | CNTF ciliary neurotrophic factor [ Homo sapiens ] |
Synonyms : | HCNTF; CNTF; Ciliary Neurotrophic Factor; OTTHUMP00000174731; ciliary neurotrophic factor. |
Gene ID : | 1270 |
mRNA Refseq : | NM_000614 |
Protein Refseq : | NP_000605 |
MIM : | 118945 |
UniProt ID : | P26441 |
Chromosome Location : | 11q12.2 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway. |
Function : | ciliary neurotrophic factor receptor binding; interleukin-6 receptor binding; protein binding. |
Products Types
◆ Recombinant Protein | ||
CNTF-2013H | Recombinant Human CNTF Protein, His-tagged | +Inquiry |
CNTF-132C | Active Recombinant Human CNTF Protein (199 aa) | +Inquiry |
Cntf-44M | Recombinant Active Mouse CNTF Protein, His-tagged(C-ter) | +Inquiry |
Cntf-434C | Active Recombinant Mouse Cntf Protein (197 aa) | +Inquiry |
Cntf-913M | Recombinant Mouse Cntf Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
CNTF-26839TH | Native Human CNTF | +Inquiry |
◆ Lysates | ||
CNTF-376HCL | Recombinant Human CNTF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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