Active Recombinant Human CNTF Protein (Met1-Met200), C-His tagged, Animal-free, Carrier-free
Cat.No. : | CNTF-16H |
Product Overview : | Recombinant Human CNTF Protein (Met1-Met200) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Ciliary neurotrophic factor (CNTF) is the member of IL-6 cytokine family and expressed in the nervous system. CNTF is 22.9 kDa neurotrophic factor containing 200 residues, which shows multiple effects in vertebrate retinogenesis. Besides, CNTF acts as a promoter that not only accelerates adult neurogenesis but also increases the survival of neuron after injury. On the other hands, reducing number of hippocampal GABAergic interneurons, as well as 5-HT levels and 5-HT1A receptor expression has been found in CNTF knockout female mice, indicating that CNTF may influence affective behavior in females by regulation of neurotransmission. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is < 0.15 μg/mL. |
Molecular Mass : | The protein has a calculated MW of 23.74 kDa. The protein migrates as 25 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Met1-Met200 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | CNTF ciliary neurotrophic factor [ Homo sapiens (human) ] |
Official Symbol : | CNTF |
Synonyms : | CNTF; ciliary neurotrophic factor; HCNTF; |
Gene ID : | 1270 |
mRNA Refseq : | NM_000614 |
Protein Refseq : | NP_000605 |
MIM : | 118945 |
UniProt ID : | P26441 |
Products Types
◆ Recombinant Protein | ||
CNTF-1157R | Recombinant Rat CNTF Protein, His (Fc)-Avi-tagged | +Inquiry |
Cntf-913M | Recombinant Mouse Cntf Protein, MYC/DDK-tagged | +Inquiry |
CNTF-435C | Active Recombinant Human CNTF Protein (199 aa) | +Inquiry |
CNTF-43H | Recombinant Active Human CNTF Protein, His-tagged(C-ter) | +Inquiry |
CNTF-132C | Active Recombinant Human CNTF Protein (199 aa) | +Inquiry |
◆ Native Protein | ||
CNTF-26839TH | Native Human CNTF | +Inquiry |
◆ Lysates | ||
CNTF-376HCL | Recombinant Human CNTF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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