Recombinant Human CLEC7A Protein, C-His-tagged
Cat.No. : | CLEC7A-130H |
Product Overview : | Recombinant Human CLEC7A Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Dectin-1 is a C-type lectin receptor expressed by macrophages, monocytes, dendrtic cells, neutrophils, and a subset of γδ T cells. Dectin-1 is a glycoprotein with eight different isoforms, generated through alternative splicing. It plays an important role in anti-fungal immunity by acting as a pattern recognition receptor for β-glucans found on the cell wall of fungi and some bacteria. Dectin-1 is composed of a short amino-terminal cytoplasmic domain containing an ITAM-like motif, a transmembrane domain, and an extracellular carboxy-terminal C-type lectin domain. Dectin-1 recognizes β-glucans through its C-type lectin domain and transduces signals through its ITAM-like motif by recruiting and activating Syk. Dendritic cells activated through Dectin-1 promote differentiation of Th17 cells by producing IL-6 and IL-23. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~21 kDa |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | CLEC7A C-type lectin domain family 7, member A [ Homo sapiens (human) ] |
Official Symbol : | CLEC7A |
Synonyms : | CLEC7A; C-type lectin domain family 7, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , CLECSF12; C-type lectin domain family 7 member A; dectin 1; hDectin 1; dectin-1; beta-glucan receptor; lectin-like receptor 1; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; BGR; CANDF4; DECTIN1; CLECSF12; |
Gene ID : | 64581 |
mRNA Refseq : | NM_022570 |
Protein Refseq : | NP_072092 |
MIM : | 606264 |
UniProt ID : | Q9BXN2 |
Products Types
◆ Recombinant Protein | ||
CLEC7A-131H | Recombinant Human CLEC7A Protein, His-tagged | +Inquiry |
CLEC7A-0624H | Recombinant Human CLEC7A Protein (T66-M247), His tagged | +Inquiry |
Clec7a-798M | Recombinant Mouse Clec7a Protein, His-tagged | +Inquiry |
CLEC7A-0623H | Recombinant Human CLEC7A Protein (T66-M247), Flag tagged | +Inquiry |
Clec7a-2204M | Recombinant Mouse Clec7a protein(Phe69-Leu244), His-tagged | +Inquiry |
◆ Lysates | ||
CLEC7A-760HCL | Recombinant Human CLEC7A cell lysate | +Inquiry |
CLEC7A-001HCL | Recombinant Human CLEC7A cell lysate | +Inquiry |
CLEC7A-2455MCL | Recombinant Mouse CLEC7A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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