Recombinant Human CLGN, His-tagged

• Cat.No.: CLGN-52H
• Product Overview: Recombinant Human Calmegin/CLGN is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu20-Trp471) of Human CLGN fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 20-471 a.a.
• Description: Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.
• AA Sequence: EFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDM DEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGI DCGGAYIKLLADTDDLILENFYDKTSYIIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPD VDLKKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWD ERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAP QILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFS ALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWVDH HHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

Gene Information

• Gene Name: CLGN calmegin [ Homo sapiens ]
• Official Symbol: CLGN
• Synonyms: CLGN; calmegin
• Gene ID: 1047
• mRNA Refseq: NM_001130675
• Protein Refseq: NP_001124147
• MIM: 601858
• UniProt ID: O14967
• Chromosome Location: 4q28.3-q31.1
• Function: calcium ion binding; unfolded protein binding