Recombinant Human CLK1 293 Cell Lysate

Cat.No. : CLK1-7441HCL
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Description : Antigen standard for CDC-like kinase 1 (CLK1), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Tag : Non
Gene Name : CLK1 CDC-like kinase 1 [ Homo sapiens ]
Official Symbol : CLK1
Synonyms : CLK1; CDC-like kinase 1; dual specificity protein kinase CLK1; CDC28/CDC2-like kinase; protein tyrosine kinase STY; CLK; STY; CLK/STY;
Gene ID : 1195
mRNA Refseq : NM_001162407
Protein Refseq : NP_001155879
MIM : 601951
UniProt ID : P49759
Chromosome Location : 2q33
Pathway : Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; mRNA processing, organism-specific biosystem;
Function : ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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    The manufacturer's commitment to customer satisfaction extends beyond technical support. They offer a comprehensive range of related products and resources to aid researchers in their trials.


      From troubleshooting to optimizing experimental protocols, the manufacturer provides diligent support to ensure the success of the trial.


        The CLK1 protein offers several advantageous features that make it an ideal choice for researchers conducting trials.

        Q&As (5)

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        How is CLK1 expression regulated in normal physiological conditions? 10/18/2020

        CLK1 expression is tightly regulated at transcriptional and post-translational levels, ensuring its proper function in normal cellular processes.

        How is CLK1 activity measured in research settings? 06/09/2020

        Researchers often measure CLK1 activity through in vitro kinase assays or by monitoring its phosphorylation targets in cellular or tissue samples.

        Can targeting CLK1 have implications for neurodegenerative diseases? 06/09/2018

        Yes, studies suggest that CLK1 inhibitors may have therapeutic potential for neurodegenerative disorders by modulating RNA splicing.

        Are there any known CLK1 mutations associated with diseases? 09/16/2017

        Some studies suggest that CLK1 mutations may be associated with certain diseases, but further research is needed to establish clear links.

        Are there any CLK1 inhibitors under development for cancer treatment? 01/21/2016

        Yes, several CLK1 inhibitors are in preclinical and clinical development as potential anticancer agents.

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