Recombinant Human CLK4 Protein, GST-tagged

• Cat.No.: CLK4-01H
• Product Overview: Recombinant human CLK4 (70-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 70-end a.a.
• Description: The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
• Molecular Mass: ~73 kDa
• Purity: > 90%
• Stability: One year at -70 centigrade from date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL
• Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Gene Information

• Gene Name: CLK4 CDC like kinase 4 [ Homo sapiens (human) ]
• Official Symbol: CLK4
• Synonyms: CLK4; CDC like kinase 4; dual specificity protein kinase CLK4; protein serine threonine kinase Clk4; EC 2.7.12.1
• Gene ID: 57396
• mRNA Refseq: NM_020666
• Protein Refseq: NP_065717
• MIM: 607969
• UniProt ID: Q9HAZ1