| Description : |
This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
186.9 kDa |
| AA Sequence : |
MAQILPVRFQEHFQLQNLGINPANI GFSTLTMESDKFICIREKVGEQAQV TIIDMSDPMAPIRRPISAESAIMNP ASKVIALKAGKTLQIFNIEMKSKMK AHTMAEEVIFWKWVSVNTVALVTET AVYHWSMEGDSQPMKMFDRHTSLVG CQVIHYRTDEYQKWLLLVGISAQQN RVVGAMQLYSVDRKVSQPIEGHAAA FAEFKMEGNAKPATLFCFAVRNPTG GKLHIIEVGQPAAGNQPFVKKAVDV FFPPEAQNDFPVAMQIGAKHGVIYL ITKYGYLHLYDLESGVCICMNRISA DTIFVTAPHKPTSGIIGVNKKGQVL SVCVEEDNIVNYATNVLQNPDLGLR LAVRSNLAGAEKLFVRKFNTLFAQG SYAEAAKVAASAPKGILRTRETVQK FQSIPAQSGQASPLLQYFGILLDQG QLNKLESLELCHLVLQQGRKQLLEK WLKEDKLECSEELGDLVKTTDPMLA LSVYLRANVPSKVIQCFAETGQFQK IVLYAKKVGYTPDWIFLLRGVMKIS PEQGLQFSRMLVQDEEPLANISQIV DIFMENSLIQQCTSFLLDALKNNRP AEGLLQTWLLEMNLVHAPQVADAIL GNKMFTHYDRAHIAQLCEKAGLLQQ ALEHYTDLYDIKRAVVHTHLLNPEW LVNFFGSLSVEDSVECLHAMLSANI RQNLQLCVQVASKYHEQLGTQALVE LFESFKSYKGLFYFLGSIVNFSQDP DVHLKYIQAACKTGQIKEVERICRE SSCYNPERVKNFLKEAKLTDQLPLI IVCDRFGFVHDLVLYLYRNNLQRYI EIYVQKVNPSRTPAVIGGLLDVDCS EEVIKHLIMAVRGQFSTDELVAEVE KRNRLKLLLPWLESQIQEGCEEPAT HNALAKIYIDSNNSPECFLRENAYY DSSVVGRYCEKRDPHLACVAYERGQ CDLELIKVCNENSLFKSEARYLVCR KDPELWAHVLEETNPSRRQLIDQVV QTALSETRDPEEISVTVKAFMTADL PNELIELLEKIVLDNSVFSEHRNLQ NLLILTAIKADRTRVMEYISRLDNY DALDIASIAVSSALYEEAFTVFHKF DMNASAIQVLIEHIGNLDRAYEFAE RCNEPAVWSQLAQAQLQKDLVKEAI NSYIRGDDPSSYLEVVQSASRSNNW EDLVKFLQMARKKGRESYIETELIF ALAKTSRVSELEDFINGPNNAHIQQ VGDRCYEEGMYEAAKLLYSNVSNFA RLASTLVHLGEYQAAVDNSRKASST RTWKEVCFACMDGQEFRFAQLCGLH IVIHADELEELMCYYQDRGYFEELI LLLEAALGLERAHMGMFTELAILYS KFKPQKMLEHLELFWSRVNIPKVLR AAEQAHLWAELVFLYDKYEEYDNAV LTMMSHPTEAWKEGQFKDIITKVAN VELCYRALQFYLDYKPLLINDLLLV LSPRLDHTWTVSFFSKAGQLPLVKP YLRSVQSHNNKSVNEALNHLLTEEE DYQGLRASIDAYDNFDNISLAQQLE KHQLMEFRCIAAYLYKGNNWWAQSV ELCKKDHLYKDAMQHAAESRDAELA QKLLQWFLEEGKRECFAACLFTCYD LLRPDMVLELAWRHNLVDLAMPYFI QVMREYLSKVDKLDALESLRKQEEH VTEPAPLVFDFDGHETRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
