Recombinant Human CNOT11 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CNOT11 Protein, Myc/DDK-tagged, C13 and N15-labeled

CNOT11 Related Products

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Cat.No. : CNOT11-820H
Product Overview : C2orf29 MS Standard C13 and N15-labeled recombinant protein (NP_060016) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 55.2 kDa
AA Sequence : MPGGGASAAS GRLLTAAEQR GSREAAGSAS RSGFGGSGGG RGGASGPGSG SGGPGGPAGR MSLTPKELSS LLSIISEEAG GGSTFEGLST AFHHYFSKAD HFRLGSVLVM LLQQPDLLPS AAQRLTALYL LWEMYRTEPL AANPFAASFA HLLNPAPPAR GGQEPDRPPL SGFLPPITPP EKFFLSQLML APPRELFKKT PRQIALMDVG NMGQSVDISG LQLALAERQS ELPTQSKASF PSILSDPDPD SSNSGFDSSV ASQITEALVS GPKPPIESHF RPEFIRPPPP LHICEDELAW LNPTEPDHAI QWDKSMCVKN STGVEIKRIM AKAFKSPLSS PQQTQLLGEL EKDPKLVYHI GLTPAKLPDL VENNPLVAIE MLLKLMQSSQ ITEYFSVLVN MDMSLHSMEV VNRLTTAVDL PPEFIHLYIS NCISTCEQIK DKYMQNRLVR LVCVFLQSLI RNKIINVQDL FIEVQAFCIE FSRIREAAGL FRLLKTLDTG ETPSETEMSK TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CNOT11 CCR4-NOT transcription complex subunit 11 [ Homo sapiens (human) ]
Official Symbol : CNOT11
Synonyms : CNOT11; CCR4-NOT transcription complex subunit 11; C40; C2orf29; CCR4-NOT transcription complex subunit 11; UPF0760 protein C2orf29
Gene ID : 55571
mRNA Refseq : NM_017546
Protein Refseq : NP_060016
UniProt ID : Q9UKZ1

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